研究課題

Inferring molecular mechanisms of neural reprogramming and maturation using single cell analysis

ルーゲッンブル ジョアヒム

ライフサイエンス技術基盤研究センター(CLST)
機能性ゲノム解析部門 細胞変換技術開発ユニット
特別研究員


TEL: MAIL:Joachim.Luginbuhl@riken.jp

I wish to adapt a single cell screening method established by Dr. Jay Shin in the Center for Life Science Technologies (CLST) in RIKEN Yokohama. This single cell screening method will be combined with CRISPR interference (CRISPRi) to perturb different sub-types of induced neurons derived by the overexpression of a defined set of neuronal transcription factors in hiPSC.

Schematic outline of the project.

Schematic outline of the project.

チームメンバー