Research Subject

Cell cycle-mediated regulation of the genetic programs that drive progression through a simple neural lineage

Adrian Moore

RIKEN Brain Science Institute
Laboratory for Genetic Control of Neuronal Architecture
Team Leader

RIKEN Brain Science Institute (BSI) 2-1 Hirosawa Wako City, Saitama 351-0198 JAPAN

Precise linking of cell cycle progression to gene expression programs in neural stem cells and precursors is essential for proper nervous system formation and for effective nervous system repair after injury. In the RIKEN-wide theme for innovation for the benefit of society, understanding these mechanisms will reveal the basis of brain tumors and neurodevelopmental diseases, and how to manipulate neural stem cells for therapy.